With the rise of nutricosmetics – products that promote beauty from within – scientifically backed probiotics are stepping into the spotlight. One such standout is Cerebiome®, a psychobiotic that’s not only changing the conversation around gut health and mental wellbeing but also delivering noticeable improvements in skin appearance and texture.
Cerebiome® is a patented psychobiotic formulation developed by the Rosell® Institute for Microbiome and Probiotics by Lallemand. It combines two highly studied probiotic strains – Lactobacillus helveticus Rosell®-52 and Bifidobacterium longum Rosell®-175 – at a clinically relevant dose of 3 billion CFU per day. Designed to support the gut-brain-skin axis, Cerebiome® offers a unique and comprehensive approach to managing stress, improving sleep, and enhancing skin health.
What sets Cerebiome® apart is not just the quality of the strains used, but the sheer volume of clinical research backing its efficacy. It is the only psychobiotic on the market with validated health claims in both Canada and Brazil, with over 10 clinical studies focused on mental health, and more than 10 preclinical studies demonstrating eight distinct mechanisms of action across the microbiome-gut-brain axis [1].
Cerebiome® supports gut health by helping to restore balance to the intestinal microbiota through its two clinically studied probiotic strains – Lactobacillus helveticus Rosell®-52 and Bifidobacterium longum Rosell®-175. These strains work synergistically to strengthen the gut barrier, reduce inflammation, and promote the production of beneficial metabolites like short-chain fatty acids. By modulating the gut microbiome, Cerebiome® helps alleviate stress-related digestive discomfort, enhances nutrient absorption, and supports overall gastrointestinal function, creating a healthier internal environment that also positively influences mental and skin health [1].
Cerebiome®’s primary function as a psychobiotic means it works to support both the gut and the mind. The gut, often referred to as the “second brain,” houses a complex community of bacteria that influences not only digestion but also mood and cognitive function [3,5]. When the balance of this microbiome is disrupted, through stress, poor diet, or illness, it can lead to gut discomfort and mental health challenges such as anxiety or poor sleep.
The combination of L. helveticus Rosell®-52 and B. longum Rosell®-175 has been shown to help restore this microbial balance and promote calm and wellbeing. In recent studies, Cerebiome® has been found to significantly reduce perceived stress, with an 18% decrease after 4 weeks and a 31% decrease after 8 weeks of daily supplementation [1].
In addition to managing stress, Cerebiome® supports better sleep quality, a vital component of both gut and skin health [3]. Participants in the clinical study reported improvements in falling asleep, staying asleep, and reduced daytime fatigue – all of which can be linked to improved gut function and microbial balance [1].
Beyond gut health and stress support, Cerebiome® is now making waves in the world of nutricosmetics, thanks to its proven ability to improve skin quality from within.
A clinical trial known as the Cosmebiome study, published in early 2025, evaluated the impact of Cerebiome® on 35 healthy women aged 30–45 over an 8-week period. Participants consumed 3 billion CFU of Cerebiome® daily, and the results were impressive [1]:
In total, 82% of women reported that their skin felt smoother and more refined, supporting the idea that Cerebiome® can visibly improve skin texture and radiance and the appearance of fine lines [1].
What makes Cerebiome® such a unique and exciting product is its multifaceted approach to health. Rather than treating gut, mind, and skin as separate systems, it recognises and supports their deep interconnection – a concept that’s gaining widespread attention in scientific communities and wellness markets alike.
By modulating the gut microbiota and reducing inflammation, Cerebiome® helps calm the nervous system, improve digestive comfort, and enhance nutrient absorption, all of which indirectly benefit the skin. Less stress means lower levels of cortisol, a hormone known to damage collagen and worsen conditions like acne, rosacea, or premature ageing.
Moreover, the improvement in sleep quality also has ripple effects on skin regeneration. Our skin undergoes its most intensive repair and regeneration processes during deep sleep, and better sleep allows for better cellular turnover, hydration retention, and collagen production [2].
These cumulative effects make Cerebiome® a strong contender for those looking for a complete inner-beauty solution – one that tackles the root causes of poor skin health rather than masking the symptoms.
Phytoceutics® Ceregut ®Probiotic is a 3 billion CFU probiotic which contains the same ingredients as Cerebiome® and contains Lactobacillus helveticus Rosell®-52 and Bifidobacterium longum Rosell®-175. Ceregut® works on the gut-brain axis to support a healthy stress response as well as improve or normalise gut bacteria, promote digestive function, and support skin health due to its influence on the gut-skin axis [4,6]. Ceregut® comes in a powder sachet with a delicious plum flavour that does not require refrigeration, has a long shelf-life, is portable, and can be conveniently taken on the go.
Cerebiome® represents a shift in holistic skincare and wellness. Rather than focusing solely on topical solutions, it offers a scientifically backed way to improve both inner wellbeing and outer beauty through the gut-brain-skin axis. With clinically proven benefits for stress, sleep, gut balance, and skin appearance, Cerebiome® is a true multitasker in the world of health and beauty. For consumers and wellness brands alike, it’s a powerful example of how the future of skincare might not come from your bathroom shelf, but from your gut.
This content is for informational purposes only and does not constitute medical advice. Always consult with your healthcare provider before starting any new supplement, especially if you are pregnant, nursing, have a medical condition, or are taking prescription or chronic medication.
